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PubMed COVID-19 Clinical Care

23061 - 23070 of 44979 results found

The immunology of PF4 polyanion interactions

Date
Monday, August 21, 2023 - 4:00 AM
Description
PURPOSE OF REVIEW: Platelet factor 4 (PF4, CXCL4), the most abundant α-granule platelet-specific chemokine, forms tetramers with an equatorial ring of high positive charge that bind to a wide range of polyanions, after which it changes conformation

Tau protein aggregation associated with SARS-CoV-2 main protease

Date
Monday, August 21, 2023 - 4:00 AM
Description
The primary function of virus proteases is the proteolytic processing of the viral polyprotein. These enzymes can also cleave host cell proteins, which is important for viral pathogenicity, modulation of cellular processes, viral replication, the

Ibuprofen, other NSAIDs and COVID-19: a narrative review

Date
Monday, August 21, 2023 - 4:00 AM
Description
At the start of the coronavirus disease 2019 (COVID-19) pandemic (March 2020), there was speculation that non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, used to manage some of the symptoms of COVID-19, could increase the