PubMed COVID-19 Clinical Care
8471 - 8480 of 44979 results found
Vaccination against COVID-19 - risks and benefits in children
Description
Countries in Europe and around the world have taken varying approaches to their policies on COVID-19 vaccination for children. The low risk of severe illness from COVID-19 means that even small risks from vaccination warrant careful consideration
Adaptation of SARS-CoV-2 to ACE2H353K mice reveals new spike residues that drive mouse infection
Description
We developed a new mouse model with a humanized angiotensin converting enzyme 2 (ACE2) locus that preserves native regulatory elements. A single point mutation in mouse ACE2 (H353K) was sufficient to confer in vivo infection with ancestral severe
A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia
Description
Pathogen clearance and resolution of inflammation in patients with pneumonia require an effective local T cell response. Nevertheless, local T cell activation may drive lung injury, particularly during prolonged episodes of respiratory failure
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines
Description
Continuous evolution of SARS-CoV-2 alters the antigenicity of the immunodominant spike (S) receptor-binding domain and N-terminal domain, undermining the efficacy of vaccines and monoclonal antibody therapies. To overcome this challenge, we set out
Insights into medical students' perceptions of work culture during the COVID-19 pandemic: a mixed method study
Description
CONCLUSIONS: The analysis highlighted the importance of students being able to adapt and draw on a range of resources during the COVID-19 pandemic. This underscores the need for work cultures that support adaptability and coping. Further research is
Epidemiology, pathogenesis, and management of Coronavirus disease 2019-associated stroke
Description
The Coronavirus disease 2019 (COVID-19) epidemic has triggered a huge impact on healthcare, socioeconomics, and other aspects of the world over the past three years. An increasing number of studies have identified a complex relationship between COVID
COVID-19 Hemiencephalitis: A Unique Manifestation
Description
No abstract
Artificial intelligence and machine learning in clinical pharmacological research
Description
CONCLUSIONS: ML, and AI in general, is increasingly being used in various research areas within clinical pharmacology. This report presents specific examples of applications and highlights the most used ML methods.
COVID vaccine-induced lupus nephritis: Case report and review of the literature
Description
Vaccines offer an effective strategy to prevent infectious diseases with minimal adverse effects. On rare occasions, vaccination can disrupt the immune response leading to induction of autoimmune diseases. We describe a case of new-onset lupus
